False


Download Learnerz IAS app from the Play Store now! Download

$show=search/label/May%202022

 


Lithocholic Acid and Lifespan Extension UPSC NOTE

SHARE:

  Lithocholic acid , a bile component , has been associated with increased lifespan in certain animal studies. In mice, its levels naturally...

 

  • Lithocholic acid, a bile component, has been associated with increased lifespan in certain animal studies.

  • In mice, its levels naturally rise during calorie restriction, which is known to promote health and longevity.

  • Lithocholic acid activates AMPK (AMP-activated protein kinase), a protein linked to the benefits of calorie restriction.

  • AMPK plays a critical role in cellular energy regulation, promoting processes that enhance health and slow aging.

Effects on Model Organisms

  • Experiments showed that nematodes and fruit flies fed lithocholic acid experienced significant lifespan extensions compared to control groups.

  • This suggests that lithocholic acid may influence conserved pathways of aging across species.

Implications for Humans

  • While these findings are promising, there is currently no evidence to suggest lithocholic acid has similar effects in humans.

  • Further research is needed to determine its safety, efficacy, and potential mechanisms in human physiology.

Future Directions

  • Investigating whether lithocholic acid or its derivatives could serve as a therapeutic intervention for age-related health decline.

  • Exploring its interaction with AMPK in human cells and its broader metabolic implications.

  • This discovery highlights the potential of bile acids as modulators of health and aging, but translating findings from animal studies to humans requires cautious and rigorous exploration.

COMMENTS

Name

Amritsar,1,April 2024,301,Art & Culture,12,August 2023,251,August 2024,400,Courses,7,Daily Current Affairs,51,December 2023,189,December 2024,340,Disaster Management,2,Environment and Ecology,348,February 2024,228,February 2025,51,Foundation Course,1,Free Class,1,GDP,1,GEMS Club,1,GEMS Plus,1,Geography,334,Govt Schemes,2,GS 2,1,GS1,101,GS2,707,GS3,559,GS4,8,GST,1,History,12,Home,3,IAS Booklist,1,Important News,71,Indian Economy,328,Indian History,27,Indian Polity,352,International Organisation,12,International Relations,277,Invasive Plant,1,January 2024,241,January 2025,350,July 2023,281,July 2024,375,June 2022,6,June 2023,268,June 2024,324,March 2024,238,May 2022,17,May 2024,330,Mentorship,2,November 2023,169,November 2024,341,Novermber 2024,2,October 2023,203,October 2024,369,Places in News,2,SC,1,Science & Technology,345,Science and Technology,121,September 2023,205,September 2024,336,UPSC CSE,115,UPSC Tips,4,
ltr
item
Learnerz IAS | Concept oriented UPSC Classes in Malayalam: Lithocholic Acid and Lifespan Extension UPSC NOTE
Lithocholic Acid and Lifespan Extension UPSC NOTE
Learnerz IAS | Concept oriented UPSC Classes in Malayalam
https://www.learnerz.in/2024/12/lithocholic-acid-and-lifespan-extension.html
https://www.learnerz.in/
https://www.learnerz.in/
https://www.learnerz.in/2024/12/lithocholic-acid-and-lifespan-extension.html
true
4761292069385420868
UTF-8
Loaded All Posts Not found any posts VIEW ALL Readmore Reply Cancel reply Delete By Home PAGES POSTS View All RECOMMENDED FOR YOU LABEL ARCHIVE SEARCH ALL POSTS Not found any post match with your request Back Home Sunday Monday Tuesday Wednesday Thursday Friday Saturday Sun Mon Tue Wed Thu Fri Sat January February March April May June July August September October November December Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec just now 1 minute ago $$1$$ minutes ago 1 hour ago $$1$$ hours ago Yesterday $$1$$ days ago $$1$$ weeks ago more than 5 weeks ago Followers Follow THIS PREMIUM CONTENT IS LOCKED STEP 1: Share to a social network STEP 2: Click the link on your social network Copy All Code Select All Code All codes were copied to your clipboard Can not copy the codes / texts, please press [CTRL]+[C] (or CMD+C with Mac) to copy Table of Content