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Semaglutide UPSC NOTE

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  Why in news Ozempic, a weight-loss drug , has become a global sensation due to its effectiveness in weight management and diabetes control...

 Why in news

  • Ozempic, a weight-loss drug, has become a global sensation due to its effectiveness in weight management and diabetes control.

  • Celebrities' endorsements and rising demand have led to supply shortages in various countries, drawing attention to its potential and challenges in accessibility.

What is Ozempic and Semaglutide

  • Semaglutide is the generic name for Ozempic (injectable) and Rybelsus (oral form), a class of drugs called  Glucagon-like peptide-1 (GLP-1) receptor agonists.

  • It works by mimicking a hormone in the body that slows digestion, reduces appetite, and stimulates insulin release, helping with weight loss and blood sugar control.

  • Ozempic was approved in 2017 for type 2 diabetes, and Wegovy (another injectable semaglutide) was approved for chronic weight management in 2021.

Concerns in India

  • Semaglutide's high price (₹10,000/month) makes it inaccessible to many in India, where out-of-pocket health expenditure is high.

  • Common side effects include nausea, bloating, and vomiting. Some patients also experience serious issues like pancreatitis.

  • Injectable forms are not yet widely available in India, leading to long wait times.

  • The drug is primarily recommended for those with obesity or type 2 diabetes, particularly those at high cardiovascular risk. It's not a first-line weight loss option.

  • There's a growing black market for semaglutide, raising concerns about misuse and unsafe self-medication.

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Learnerz IAS | Concept oriented UPSC Classes in Malayalam: Semaglutide UPSC NOTE
Semaglutide UPSC NOTE
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Learnerz IAS | Concept oriented UPSC Classes in Malayalam
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