Why in news
Researchers at UC San Francisco and UC Davis identified a novel brain-derived hormone linked to increased bone mass in postpartum lactating mothers.
The hormone is called CCN3.
What is Osteoporosis
Bone is living tissue that is constantly being broken down and replaced.
Osteoporosis occurs when the creation of new bone doesn't keep up with the loss of old bone
Osteoporosis is a condition in which the body’s bones become weak and brittle.
As bones become more porous and fragile, the risk of fracture is greatly increased
There are more than 10 million cases of osteoporosis every year in India, and it disproportionately affects ageing women more than men.
The hormone oestrogen plays a crucial role in this condition because it stimulates the growth and formation of new bone.
After menopause, the decreased function of the ovaries leads to oestrogen being depleted in the body, resulting in the loss of bone mass.
Symptoms: Often there are no symptoms until the first fracture occurs as the loss of bone occurs silently and progressively.
Diagnosis: A bone mineral density (BMD) test measures how much calcium and other types of minerals are in an area of a bone.
This test helps health care provider detect osteoporosis and predict the risk for bone fractures.
Prevention: Good nutrition with adequate calcium, protein, and Vitamin D as well as regular exercise can help in keeping bone healthy throughout the life.
Function of Hormone CCN3
CCN3, a hormone produced in the hypothalamus, helps increase bone mass by enhancing the maturation and activity of skeletal stem cells, leading to stronger bones.
During postpartum lactation, CCN3 supports bone mineralization and compensates for the lack of estrogen, contributing to increased bone mass in lactating mothers.
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