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Clade 1b UPSC NOTE

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  Why in news Mpox is declared a Public Health Emergency of International Concern (PHEIC) by WHO for the second time due to its spread fro...

 Why in news

  • Mpox is declared a Public Health Emergency of International Concern (PHEIC) by WHO for the second time due to its spread from the Democratic Republic of the Congo (DRC)  to multiple African countries.

  • The outbreak is now driven by Clade 1b, a more lethal variant of the mpox virus.

Clade 1b

  • Mpox is separated into two different clades: clade I and clade II.

  • The more virulent and deadlier clade I is endemic in the Congo Basin in central Africa

  • Clade II is endemic in West Africa.

  • Clade I strains cause more severe illness and deaths, with mortality rates of around 3%.

  • But the mortality rate from strain clade 1b can be as high as 10% among children.

  • The clade 1b strain causes skin rashes across the whole body, unlike other strains where lesions and rashes are usually limited to the mouth, face and genitals.

  • It spreads effectively through both sexual and non-sexual contact

What is endemic means 

  • A disease is considered endemic when it regularly occurs in a specific geographic area or population

  • Mpox is described as endemic in Africa, meaning it regularly occurs there despite occasional outbreaks.

  • When the cases begin to rise, it is classified as an epidemic. 

  • If this epidemic has been recorded in several countries and areas, it is called a pandemic.

  • Some examples of endemics include chicken pox and malaria, where there are a predictable number of cases every year in certain parts of the world


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Learnerz IAS | Concept oriented UPSC Classes in Malayalam: Clade 1b UPSC NOTE
Clade 1b UPSC NOTE
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https://lh7-rt.googleusercontent.com/slidesz/AGV_vUfA1MEQCGPdBnPJXRN2U47jt2o1PH0uzpi2wPp2FznCa6zKMsgP1HGZaUfCp8I4xxJiyCClViKafwLPZnd4v2IO1mUf6MqwQVtThHEu_KL5-H7xv7w5mNBCRg9ThVHGmLAUfoh4H8ZzGwLlYCzJ9Hf_Ft_Zi5fIloQ9wkni7lVu8w=s72-c?key=M2EMdh98SSRXlQWZvbbVAw
Learnerz IAS | Concept oriented UPSC Classes in Malayalam
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